The widening spectrum of immunological memory

The widening spectrum of infectious neurological disease.

[The widening challenge of extended spectrum β-lactamases].

Since 1980, the prescription of new semi-synthetic molecules of third generation cephalosporins changed the course of modern medicine. However, the acquired resistance against these antibiotics was rapidly developed with the production of extended spectrum β-lactamases (ESBL) (TEM and SHV types) disseminated mainly by nosocomial Klebsiella pneumoniae clones. Since around 2000, we are facing a w...

The widening spectrum of neurological damage in liver disease.

T Rays vs. Terrorists: Widening the Security Spectrum

Summanr Low-density lipoprotein (LDL) uptake in gliomas was studied to find out if LDL has potential as a drug camrer of boron. especially for boron neutron capture therapy. Single photon emission tomography (SPET) was performed 2 h and 20 h after intravenous injection of autologous 9"9Tc-labelled LDL in four patients with untreated and five patients with recurrent glioma. 9'Tc-LDL uptake was c...

Mitochondrial DNA defects: a widening clinical spectrum of disorders.

1. Mitochondrial DNA has a number of interesting properties including maternal transmission, the ability to replicate in post-mitotic cells, a high mutation rate and an extremely compact molecular architecture with no introns and no large non-coding sequences. 2. Point mutations, deletions and duplications of mitochondrial DNA may occur. Mitochondrial DNA defects may co-exist with wild-type seq...